Urano Laboratory
Laboratory of Chemical Biology and Molecular Imaging
The University of Tokyo
--- RESEARCH ---
研究テーマ
生細胞内、動物個体内で起こる様々なイベントを、高感度に可視化する有機小分子蛍光プローブの設計・合成・開発を中心としたケミカルバイオロジー研究を行う研究室です。外科医との共同研究を含め、がん部位の検出を可能とする蛍光プローブの創製による術中迅速診断技術や、新規抗がん剤の開発などを行っています。また、機能性タンパク質や細胞・細胞外小胞などを組み合わせた次世代医療技術の開発研究も行っています。
新規蛍光プローブ、増感剤、抗がん剤、ケージド化合物、ラマンプローブ の開発
開発した機能性プローブの生物応用・がんのイメージングと治療
機能性タンパク質や細胞・細胞外小胞なども組み合わせた、次世代医療技術の開発
OUR RESEARCH
Our research group focuses on the design, synthesis, and development of small molecular chemical probes for biological and medical research. These include fluorescent probes for visualizing various events occurring in living cells and animals. We are also collaborating with medical surgeons to establish an intraoperative diagnostic technique by using our fluorescent probes for rapid and sensitive detection of tumor site. Moreover, we are also interested in developing new therapeutics based on synergistic use of functional small molecules, proteins, cells, and extracellular vesicles.
・Development of novel fluorescent probes, sensitizers, anti-cancer drugs, caged compounds, and Raman probes.
・Biological applications and imaging of functional probes developed and their use in cancer treatment.
・Development of next-generation medical technologies by combining functional proteins, cells, and extracellular vesicles.
Copyright (C) Laboratory of Chemical Biology and Molecular Imaging Graduate School of Medicine, The University of Tokyo.