Our research field is so-called chemical biology. One of our main research interests is to develop novel small molecule-based photo-functional tools for biological and medical research, including fluorescence probes for detecting various events in living cells and animals. Recently, we have succeeded to develop fluorescence probes for in vivo tumor detection, and they are now applied to real resected human samples by collaborating with many surgeons.
- Establishment of rational design strategies for various photo-functional small molecule-based probes
- Development of novel fluorescence probes, photosensitizing probes and caged compounds, and their application to various living biological samples
- In vivo detection and therapy of tumors in model mice and real human samples by using rationally designed novel fluorescence and photosensitizing probes